https://ajls.journals.unisel.edu.my/index.php/ajls/issue/feed 2024-05-20T23:56:57+08:00 Fridelina Sjahrir fridelina@unisel.edu.my Open Journal Systems <p><strong>Welcome to the Asean Journal of Life Sciences (AJLS)</strong></p> <p>The Asean Journal of Life Sciences (AJLS) is a peer-reviewed journal and dedicated to publish and disseminate original articles in all areas of Biology and Life Sciences. The emphasis will be on publishing very quick quality research papers and would be freely available to researchers worldwide. It is an open access journal, which publishes original research articles, reviews and short communication. The scopes of the journal include, but not limited to the following topic areas: Biology, Life Science, Anatomy, Botany, Cytology, Genetics, Microbiology, Physiology, Zoology, Ecology, Environmental Science, Hydrobiology, Neurobiology, Developmental Biology, Immunology, Molecular Biology, Biochemistry, Biophysics, and Biotechnology, Biomedical, pharmacology, Agriculture, Fisheries, Aquaculture, Pharmacy, Plant Sciences, Virology, Toxicology, Immunology, Genomics, Proteomics and Bioinformatics.</p> https://ajls.journals.unisel.edu.my/index.php/ajls/article/view/40 2024-05-20T23:56:57+08:00 Roshani Othman roshaniothman@hotmail.com Farrah Nazuha Mansor farah_nazuha@unisel.edu.my Nur Akmal Suliman nurakmal@unisel.edu.my Jessinta Maria Ganam Puspanathan roshani@unisel.edu.my Norazah Mohammad Nawawi norazah@unisel.edu.my Mohd Syahril Mohd Zan roshani@unisel.edu.my

<p>Arthrospira platensis is a cyanobacteria with the ability to produce a large amount of antimicrobial substances, making it a suitable microorganism for use as a biocontrol agent for pathogenic bacteria. In this research, different amounts of A. platensis extracts grown outside (100 μg/μL, 50 μg/μL, and 25 μg/μL) were tested for their ability to kill five types of bacteria: <em>Escherichia coli, Bacillus subtilis, Proteus vulgaris, Salmonella enterica,</em> and <em>Staphylococcus aureus</em>. The tests were done using methanol, aqueous, and chloroform as solvents. The disc diffusion and serial micro-dilution techniques were used to determine the inhibition zone and minimum inhibitory concentration (MIC) of the pathogen bacteria, respectively. The results showed that <em>A</em>. <em>platensis</em> extracts significantly inhibited the growth of <em>E.</em> <em>coli</em>, with inhibition zones of 24.00 ±1.51 mm, 18.00 ± 0.15 mm and 15.00±0.12 mm at concentrations of 100 μg/μL, 50 μg/μL, and 25 μg/μL, respectively. At the highest concentration, the effect is comparable to that of tetracycline (30 μg). Methanol and aqueous extracts with MIC values of 100-200 μg/μL demonstrate antibacterial properties. However, <em>A. platensis</em> extracts did not significantly inhibit the growth of <em>P. vulgaris, S. enterica,</em> or <em>S. aureus</em>. In conclusion, the findings of this study demonstrated that outdoor-cultured <em>A</em>. platensis extracts could be a good source for the production of promising antimicrobial agents.</p>

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